The College of Science, Mustansiriyah University discussed Ph.D. thesis on the antioxidant activity of a gold-platinum nanohybrid prepared using broccoli extract and explored its anti-cancer properties by postgraduate student, Mr. Yasser Mohammed Khalil.
The thesis aimed at synthesizing a gold-platinum binary nanohybrid using an aqueous extract of broccoli and exploring its hybrid properties and potential applications in cancer treatment and wound healing.
The thesis adopted a green approach to synthesizing the gold-platinum nanohybrid using an aqueous extract of broccoli to achieve higher biocompatibility and reduce the high toxicity of platinum.
The thesis covered the preparation, characterization, and biochemical evaluation of the nanohybrid, assessing its antibacterial and antioxidant activity, and evaluating its role in wound healing and combating HepG2 human liver cancer cells.
The thesis highlighted a slight decrease in the effectiveness of the nanohybrid compared to nanoplatinum, while achieving a significant increase in biocompatibility to reduce the high toxicity of platinum while maintaining its activity in inhibiting bacteria and eliminating cancer cells and the nanohybrid recorded higher effectiveness than nano platinum in the field of wound healing.
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