College of Medicine, University of Babylon discussed a Ph.D. thesis on the chemical and molecular effect of Calectin and its receptors in rheumatoid arthritis by the postgraduate student, Mr. Ahmed Jabbar Abbas.

The thesis reviewed a biochemical and molecular study of calectin-3, chemokine-2 Gene, and its receptors in patients with rheumatoid arthritis and its effect on the transmission of the genetic change (A/G) at position -2518 of the CCL2 Gene, which was linked to the susceptibility to the development of the disease.

The thesis highlighted that the genetic variations associated with CCL2 and the effect of the transmission of the genetic change (A/G) at position -2518 of the CCL2 Gene were linked to the susceptibility to developing rheumatoid arthritis.

The thesis demonstrated that there was a significant positive correlation between the concentration of VEGF and the concentration of CCR2 (P. value = 0.001, R2 = 0.175) and the concentration of CCL2 (P. value = 0.041, R2 = 0.00939), respectively, in the patient group.