College of Biotechnology, Al-Nahrain University discussed a master dissertation on the antibacterial and anti-biofilm activity of levofloxacin against pathogenic staphylococcus epidermidis by the postgraduate student, Ms. Safa Zuhair Ghazi.

The dissertation aimed at evaluating the effectiveness of the antibiotic levofloxacin in combating staphylococcus epidermidis, highlighting its effect in reducing the biofilms produced by these bacteria and studying the gene expression associated with their resistance to drugs, which contributes to the development of more effective treatment strategies.

The dissertation included an analysis of the behavior of staphylococcus epidermidis when exposed to different concentrations of levofloxacin.

The dissertation demonstrated that these bacteria contain genes associated with virulence and resistance to treatment, and that exposure to concentrations below the minimum inhibitory limit may stimulate the production of biofilms, which increases the severity of infection and the difficulty of treatment.

The dissertation stressed the importance of understanding the mechanisms of resistance of staphylococci to antibiotics to help improve treatment policies and reduce the risks of associated infections.