College of Biotechnology, Al-Nahrain University discussed a master dissertation on virulence determinants blaACT and blaACC among clinically isolated Proteus bacteria by the postgraduate student, Ms. Nour Mohammed Jassim.

The dissertation aimed at clarifying the problem of bacterial resistance to antibiotics, focusing on Proteus mirabilis, which is one of the main causes of infections in hospitals and poses an increasing challenge in the health field due to its increasing resistance to drugs.

The dissertation stressed the need to monitor the development of bacterial resistance to antibiotics.

The dissertation reviewed that 20% of the isolates were multiple drug resistance (XDR), with complete resistance to some antibiotics such as gentamicin and tigecycline, while they showed sensitivity to ertapenem genetic tests also showed the prevalence of the aac(6’)-Ib gene in all isolates and when the plasmids were neutralized, the resistance rate decreased by 50%.