College of Science, University of Al-Mustansiriyah discussed a master dissertation on the neurological, immunological and physiological indicators and their relation to autism spectrum disorder by the postgraduate student, Mrs. Russell Aboud Alwan. The dissertation reviewed the neurological, immune and physiological changes in children with autism and identifying the vital signs that contribute to diagnose disorders. The dissertation conducted analyzes of some cytokines, neurotransmitters, complete blood picture and cortisol hormone on (50) cases of children with severe, moderate and mild autism. The dissertation concluded that there is a decrease in the level of kappa and dopamine, an increase in serotonin in children with autism, and an increase in the level of tumor necrosis factor, as well as a comprehensive analysis of the levels of peripheral cytokines provides a new approach in improving the diagnosis of children with autism.